Lazio seem forced to continue with the same starting line-up, as Atalanta stay with Papu Gomez and Duvan Zapata in attack.
The match kicks off at 19.45 UK time.
The Aquile coach Simone Inzaghi will have to cope without defenders Luiz Felipe and Denis Vavro and will have to wait until after the international break to see Wesley Hoedt available.
The Biancocelesti will most likely turn up with the same XI from the 2-0 win against Cagliari last time, meaning Joaquin Correa should start with Ciro Immobile up front.
Atalanta coach Gian Piero Gasperini seems set to trust his old players when the Orobici travel to the capital, as Cristian Romero has recovered but should be on the bench.
Berat Djimsiti will return to the starting line-up with Rafael Toloi and Jose Luis Palomino in defence, without any changes in the midfield.
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Gasp confirmed Sam Lammers is not ready to start, as Gomez and Zapata are expected continue in attack. Luis Muriel and Ruslan Malinovskyi fight for the last place.
Lazio (probable): Strakosha; Patric, Acerbi, Radu; Lazzari, Milinkovic-Savic, Lucas Leiva, Luis Alberto, Marusic; Correa, Immobile
Atalanta (probable): Sportiello; Toloi, Palomino, Djimsiti; Hateboer, De Roon, Freuler, Gosens; Gomez; Zapata, Muriel
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